Biomedika
Vol 16, No 2 (2024): Biomedika Agustus 2024

The Effect of Zinc Supplementation on Malondialdehyde (MDA) Levels in First Year Students of The Faculty of Medicine Universitas Pattimura

Tuanaya, Syafira Arfani (Unknown)
Angkejaya, Ony W (Unknown)
de Lima, Filda Vionita Irene (Unknown)
Abbas, Mutmainnah (Unknown)
Tamalsir, Dylan (Unknown)
Sulfiana (Unknown)



Article Info

Publish Date
23 Oct 2024

Abstract

An imbalance between free radicals and antioxidants in the body causes a condition called oxidative stress, which can be caused by several factors, one of which is psychological stress. Various studies have shown that medical students tend to experience psychological stress, especially in first year. Psychological stress tends to increase SO conditions due to increased ROS and free radicals in the body. Zinc can reduce ROS and free radicals through several mechanisms. This study aims to determine the effect of zinc supplementation on MDA levels in first year students of the Faculty of Medicine. This study used a true experimental analytic study with pretest-posttest control group design. The sample amounted to 22 people in intervention group and 22 people in control group. This study used TBARS method to measure MDA levels. The results showed a decrease in MDA levels in intervention group (p=0.000), while in the control group there was an increase in MDA levels (p=0.006). In addition, lower MDA levels were found in intervention group compared to control group measured after 10 days (p=0.000). This study concluded that there was an effect of Zinc supplementation on MDA levels in first year students of the Faculty of Medicine, Pattimura University.

Copyrights © 2024






Journal Info

Abbrev

biomedika

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology

Description

Biomedika is one of the efforts of the Faculty of Medicine of University Muhammadiyah Surakarta to improve the academic atmosphere, as a publication of research results from lecturers and students. The existence of Biomedika is expected to enhance the activity and quality of research in medical and ...