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Mutmainnah Abbas
Universitas Pattimura, Ambon
Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Dentistry Environmental Science Medicine & Pharmacology

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The Effect of Zinc Supplementation on Malondialdehyde (MDA) Levels in First Year Students of The Faculty of Medicine Universitas Pattimura Syafira Arfani Tuanaya; Ony W Angkejaya; Filda Vionita Irene de Lima; Mutmainnah Abbas; Dylan Tamalsir; Sulfiana
Biomedika Vol 16, No 2 (2024): Biomedika Agustus 2024
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v16i2.5877

Abstract

An imbalance between free radicals and antioxidants in the body causes a condition called oxidative stress, which can be caused by several factors, one of which is psychological stress. Various studies have shown that medical students tend to experience psychological stress, especially in first year. Psychological stress tends to increase SO conditions due to increased ROS and free radicals in the body. Zinc can reduce ROS and free radicals through several mechanisms. This study aims to determine the effect of zinc supplementation on MDA levels in first year students of the Faculty of Medicine. This study used a true experimental analytic study with pretest-posttest control group design. The sample amounted to 22 people in intervention group and 22 people in control group. This study used TBARS method to measure MDA levels. The results showed a decrease in MDA levels in intervention group (p=0.000), while in the control group there was an increase in MDA levels (p=0.006). In addition, lower MDA levels were found in intervention group compared to control group measured after 10 days (p=0.000). This study concluded that there was an effect of Zinc supplementation on MDA levels in first year students of the Faculty of Medicine, Pattimura University.
Body fat distribution, lipid profile and cardiometabolic risk factors in perimenopause Rosdiana Mus; Elpira Asmin; Ingrid Hutagalung; Mutmainnah Abbas; Genevieva Tanihatu; Jansye Cynthia Pentury
Media Penelitian dan Pengembangan Kesehatan Vol. 36 No. 3 (2026): MEDIA PENELITIAN DAN PENGEMBANGAN KESEHATAN
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/jmp2k.v36i3.4478

Abstract

Background: Body fat correlates with increased risks of metabolic and cardiovascular diseases, Young women are at a heightened risk for metabolic syndrome linked to dyslipidemia, which contributes to atherosclerosis. Objective: The aimed of study is correlation between body fat distribution, lipid profiles, and cardiometabolic risk factors in perimenopause women with age-specific Methods: A total of in 103 participants aged 35-55 years were included in this cross-sectional study with consecutive sample method. Participants were classified perimenopause women aged <45 and ≥45 years old. Body fat distribution used a Bioelectrical Impedance Analysis, Blood pressure used a sphygmomanometer and lipid profiles by lipid monitoring system by finger prick. Statistical analysis including independent sample t-tests, correlation analysis using pearson correlation test for normally and the Spearman correlation for non-normalyy distributed data.. Results: The results showed that there were differences in characteristics in two groups like WC (89.9±11.4 vs 96.1±9.8), systolic (132.7±23.3 vs 143±23.2), total cholesterol (170.5±39.8 vs 208.3±37.1), HDL-C (42.7±13.3 vs 50.69±14.8), LDL-C (105.7±28.1 vs 122.6±29.9) and TG (128.2±52.8 vs 170.6±74.9). Correlation analysis demonstrated positive correlation between of age with WC, systolic and lipid profiles. WC have a positive correlations with visceral fat and total fat, systolic and diastolic. Diastolic pressure positively correlated with total fat and visceral fat, with a strong correlation with systolic. Age,TC and TG correlated positively with WC and systolic, with LDL showing a similar correlation Conclusion: Research shows a significant association with several cardiovascular risk factors. These risk factors increases the risk of cardiovascular disease.
Co-Authors Dylan Tamalsir Elpira Asmin Filda Vionita Irene de Lima Genevieva Tanihatu Ingrid Hutagalung Jansye Cynthia Pentury Ony W Angkejaya Rosdiana Mus Sulfiana Syafira Arfani Tuanaya