Journal of Applied Pharmaceutical Research
Vol. 12 No. 5 (2024)

A pharmacognostic, phytochemical, and antioxidant potential of Oxalis triangularis

Sharma, S. (Unknown)
Bhuyan, N. R. (Unknown)
Mohanty, J. P. (Unknown)



Article Info

Publish Date
31 Oct 2024

Abstract

Background: To evaluate Oxalis triangularis with pharmacognostical parameters (macroscopy, microscopy & physico-chemical analysis), phytochemical analysis, and to investigate the in-vitro antioxidant capacity of different extracts obtained. Methods: Using specific standard protocols, the following tests were performed: loss on drying, extractive value, ash value, t.s. & powder microscopy, fluorescence analysis, and phytochemical screening. The Folin-Ciocalteu technique was adopted to ascertain the amount of phenolic compounds. In-vitro antioxidant activity was evaluated using 2,2-diphenyl-1-picryl-hydrazyl-hydrate (DPPH)  & 2,2'-Azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical scavenging assays. Results: The extractive values varied between solvents, ranging from 1.28% (ethyl acetate) to 18.8% (water), while the ash values were 16.25% (total), 2.9% (acid insoluble), and 10.625% (water-soluble). Numerous vascular systems, lignified trichomes, and calcium oxalate crystals were visible under a microscope. Saponins, steroids, flavonoids, phenols, anthocyanins, and alkaloids were detected by phytochemical screening; glycosides were not detected. At 200 µg/ml, the phenolic concentration of the ethanolic extract was the highest, at 1151.7 ± 59.22 µg/ml. The ethanolic extract exhibited greater DPPH (IC50 = 2.403 µg/ml) and ABTS (IC50 = 22.94 µg/ml) radical scavenging activity in comparison to the aqueous extract, i.e., (DPPH, IC50= 76.67 µg/ml & ABTS, IC50= 43.52 µg/ml). In contrast, both extracts showed notable antioxidant activity. Conclusion: A comprehensive examination of Oxalis triangularis revealed a rich reservoir of bioactive chemicals, such as phenols, which make the plant rich in antioxidant properties. This may serve as a foundation for the discovery of novel medicines.

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Journal Info

Abbrev

joapr

Publisher

Subject

Medicine & Pharmacology

Description

Journal of Applied Pharmaceutical Research (JOAPR) is an official publication of Creative Pharma Assent (CPA). It is an open access, peer review online international journal. JOAPR is primarily focused on multiple discipline of pharmaceutical sciences (Pharmaceutics, Pharmaceutical Technology, ...