Bali Medical and Wellness Journal
Vol. 1 No. 2 (2024): Bali Medical and Wellness Journal

Systematic Review: Effectiveness of Probiotic Giving as Additional Therapy in Atopic Dermatitis Patient

Pangkahila, Evangelista Maria (Unknown)
Dewi, Made Yudha Asrithari (Unknown)
Harimawan, Agustinus I Wayan (Unknown)



Article Info

Publish Date
27 Nov 2024

Abstract

Background: Atopic dermatitis (AD), also known as eczema, is a chronic inflammatory skin condition affecting the epidermis and dermis. It is triggered by a combination of environmental and genetic factors, leading to symptoms such as polymorphic rashes and intense itching. Objective: This systematic review aims to evaluate the effectiveness of oral probiotic supplementation as an adjunct therapy for individuals with atopic dermatitis. Methods: The literature was reviewed by searching two electronic databases, Google Scholar and PubMed, resulting in the inclusion of eight studies that collectively involved 347 AD patients. Results: The findings indicate that probiotic supplementation can significantly reduce the severity and incidence of atopic dermatitis. This effect is attributed to the inhibition of Th2 cell activity and a reduction in pro-inflammatory cytokines, including TNF-α and IgE, which are known contributors to the pathophysiology of AD. Conclusion: Probiotics present a promising alternative for the prevention and management of atopic dermatitis, potentially enhancing patient outcomes.

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Journal Info

Abbrev

bmwj

Publisher

Subject

Dentistry Health Professions Medicine & Pharmacology Nursing Public Health

Description

The Bali Medical and Wellness Journal is an internationally open-access, peer-reviewed journal that aims to disseminate high-quality research and knowledge related to medical sciences and wellness practices fostering a holistic approach to health, integrating physical, mental, and social well-being. ...