MPSJ
Vol 1 No 2 (2023)

Uji Aktivitas Antibakteri Ekstrak Etanol Daun Kayu Jawa (Lannea coromandelica (Houtt.) Merr.) Terhadap Bakteri Penyebab Infeksi Saluran Pencernaan Dengan Metode Difusi Agar

Rahmawati Rabbana (Universitas Muslim Indonesia)
Rachmat Kosman (Unknown)
Siska Nuryanti (Unknown)



Article Info

Publish Date
04 Sep 2023

Abstract

The purpose of this research was to determine the antibacterial activity of the ethanol extract of Javanwood leaves Lannea coromandelica (Houtt.) Merr.) against bacteria that cause digestive tract infections. The research method begins with the extraction process using the maceration method with 96% ethanol solvent and evaporated using a rotary evaporator. Java wood leaf ethanol extract was subjected to screening tests with a concentration of 0.1%; 0.5%; and 1% against the test bacteria Eschericia coli, Salmonella typhi, Shigella dysenteriae and Vibrio cholerae. MIC and MBC tests were carried out and continued with antibacterial activity tests using the agar diffusion method with variations in concentrations of 0.5%; 1%; 2%; 4%; 8%; and 16%. The results of the screening test for Escherichia coli and Shigella dysenteriae bacteria at 0.5%. MIC values for Escherichia coli bacteria at 0.125% and Shigella dysenteriae bacteria at 2%. While the MBC value for Escherichia coli bacteria is at 0.5% and Shigella dysenteriae bacteria at 2%. The results of testing the antibacterial activity of the ethanol extract of Javanwood leaves against Escherichia coli and Shigella dysenteriae bacteria had the largest diameter of the inhibition zone at a concentration of 16%, respectively 17.10 mm; and 13.56 mm which is included in the criteria of having strong inhibition. Based on the results of the ethanol extract of Javanwood leaves, it has potential as an antibacterial.

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Journal Info

Abbrev

mpsj

Publisher

Subject

Medicine & Pharmacology

Description

Makassar Pharmaceutical Science Journal merupakan salah satu jurnal yang dikelola oleh Fakultas Farmasi Universitas Muslim Indonesia yang terbit pertama kali pada bulan Maret 2023. Makassar Pharmaceutical Science Journal merupakan jurnal ilmiah yang terbit secara on-line dan menerbitkan artikel atau ...