Physical Sciences, Life Science and Engineering
Vol. 2 No. 3 (2025): June

Exploring the Principles of GC-MS: Techniques and Applications

Khalifea, Hassan (Unknown)
Ali, Noor (Unknown)



Article Info

Publish Date
08 Apr 2025

Abstract

GC-MS operates as a robust analytical method that chemistry labs commonly use because it effectively separates chemicals while identifying their components with precise accuracy. Research instruments like GC-MS provide high quality separation and molecular identification which makes them indispensable for environmental studies as well as pharmaceutical insights and forensic investigations and quality control applications. Extensive usage of GC-MS remains incomplete because researchers must develop an organized framework which illustrates system elements and their supporting functions together with application boundaries. The main objective of this research is to establish a systematic examination of GC-MS core functioning and equipment alongside examining operational details and system constraints. The research shows how GC-MS components including injectors, columns, ionization techniques, mass analyzers and detectors function together to achieve optimal performance results. The research presents current uses of GC-MS in environmental monitoring and pharmaceutical analysis and forensic science through methodological examples while supplying reference spectra. This comprehensive study combines GC-MS principles with practice to provide a unified framework which includes reviews regarding recently developed hyphenated methods and ionization approaches and column development. The research results function as a useful guide for scientists as well as practitioners to help them select systems properly and develop methods and advance GC-MS systems for intricate analytical tasks.

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Journal Info

Abbrev

pslse

Publisher

Subject

Humanities Engineering Physics Social Sciences

Description

Explore the Physical Sciences, Life Science and Engineering. This section accommodates research papers that aim to present the practical aspects of certain theoretical hypotheses reflected through empirical approach to problemsolving, systematic methodology that guarantee the validity of research ...