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All Journal Physical Sciences, Life Science and Engineering Magenta Journal De Healthymedi
Ali, Noor
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Humanities Engineering Health Professions Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary

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Exploring the Principles of GC-MS: Techniques and Applications Khalifea, Hassan; Ali, Noor
Physical Sciences, Life Science and Engineering Vol. 2 No. 3 (2025): June
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/pslse.v2i3.388

Abstract

GC-MS operates as a robust analytical method that chemistry labs commonly use because it effectively separates chemicals while identifying their components with precise accuracy. Research instruments like GC-MS provide high quality separation and molecular identification which makes them indispensable for environmental studies as well as pharmaceutical insights and forensic investigations and quality control applications. Extensive usage of GC-MS remains incomplete because researchers must develop an organized framework which illustrates system elements and their supporting functions together with application boundaries. The main objective of this research is to establish a systematic examination of GC-MS core functioning and equipment alongside examining operational details and system constraints. The research shows how GC-MS components including injectors, columns, ionization techniques, mass analyzers and detectors function together to achieve optimal performance results. The research presents current uses of GC-MS in environmental monitoring and pharmaceutical analysis and forensic science through methodological examples while supplying reference spectra. This comprehensive study combines GC-MS principles with practice to provide a unified framework which includes reviews regarding recently developed hyphenated methods and ionization approaches and column development. The research results function as a useful guide for scientists as well as practitioners to help them select systems properly and develop methods and advance GC-MS systems for intricate analytical tasks.
The Therapeutic Strategies for Eliminating Biofilm Produced by Staphylococcus Aureus Isolated from Catheter by Exposing to Radiation Emitted from Radioactive Sources (In Vitro) Mohammed, Nebras Rada; Ali, Noor
Magenta Journal De Healthymedi Vol. 1 No. 2 (2024): Magenta Journal De Healthymedi
Publisher : Generasi Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/mjdh.v1i2.45

Abstract

This study aimed to evaluate the effectiveness of Sr90 radiation in eliminating biofilm production and inhibiting the growth of Staphylococcus aureus, a Gram-positive, facultative anaerobic bacterium responsible for infections such as pneumonia, sepsis, and bacteremia, whose virulence is enhanced by biofilm formation. A cross-sectional descriptive design combined with a case–control analytical approach was employed, with bacterial isolates obtained from catheters and other clinical samples of patients in Baghdad hospitals during 2023–2024. Biofilm-producing S. aureus isolates were exposed to varying doses of Sr90 radiation, with and without aluminum shielding, and their biofilm activity was assessed using Congo-Red Agar before and after exposure. Results demonstrated that all isolates (100%) exhibited biofilm production prior to treatment; however, after exposure to Sr90, biofilm production was completely inhibited (0%), as indicated by red colony coloration on Congo-Red Agar. Furthermore, Sr90 exposure produced 100% bactericidal activity across increasing doses and time intervals, whether aluminum shielding was applied or not. These findings provide evidence that Sr90 radiation effectively disrupts biofilm production and eradicates S. aureus, highlighting its potential as an innovative therapeutic strategy for managing biofilm-associated infections.
Co-Authors Khalifea, Hassan Mohammed, Nebras Rada