Paediatrica Indonesiana
Vol 46 No 4 (2006): July 2006

Relation of bleeding patterns and factor VIII levels in children with hemophilia

Rina Rahardiani (Unknown)
H. S. Moeslichan MZ (Unknown)
Agus Firmansyah (Unknown)



Article Info

Publish Date
18 Oct 2016

Abstract

Background The high costs of factor VIII examination cause thedelay in the diagnosis of hemophilia A; consequently many pa-tients do not receive adequate therapy which results in failure tosurvive into adulthood or survive with creeple.Objective To determine bleeding patterns of hemophilia A pa-tients for the prediction of its classification.Methods We perform retrospective analysis of hemophilia patientsat the Integrated Service Center of Hemophilia, Cipto Mangun-kusumo Hospital, Jakarta.Results Family history, age at the first bleeding, frequency of bleed-ing, and factor VIII examination can significantly differentiate theclassification of hemophilia A (P=0.015; 0.014; <0.0001; and<0.0001, respectively) while age groups, triggering trauma for thefirst bleeding, type of the first bleeding, history of previous trauma,the most frequent type of bleeding, age at diagnosis, and con-sumption of cryoprecipitate cannot. (P=0.985; 0.475; 0.342; 0.318;0.058; 0.477; and 0.547, respectively).Conclusion Age at first bleeding, frequency of bleeding, and fam-ily history can be used to predict classification of hemophilia A.

Copyrights © 2006






Journal Info

Abbrev

paediatrica-indonesiana

Publisher

Subject

Health Professions Medicine & Pharmacology

Description

Paediatrica Indonesiana is a medical journal devoted to the health, in a broad sense, affecting fetuses, infants, children, and adolescents, belonged to the Indonesian Pediatric Society. Its publications are directed to pediatricians and other medical practitioners or researchers at all levels of ...