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H. S. Moeslichan MZ
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Health Professions Medicine & Pharmacology

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Relation of bleeding patterns and factor VIII levels in children with hemophilia Rina Rahardiani; H. S. Moeslichan MZ; Agus Firmansyah
Paediatrica Indonesiana Vol 46 No 4 (2006): July 2006
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi46.4.2006.159-63

Abstract

Background The high costs of factor VIII examination cause thedelay in the diagnosis of hemophilia A; consequently many pa-tients do not receive adequate therapy which results in failure tosurvive into adulthood or survive with creeple.Objective To determine bleeding patterns of hemophilia A pa-tients for the prediction of its classification.Methods We perform retrospective analysis of hemophilia patientsat the Integrated Service Center of Hemophilia, Cipto Mangun-kusumo Hospital, Jakarta.Results Family history, age at the first bleeding, frequency of bleed-ing, and factor VIII examination can significantly differentiate theclassification of hemophilia A (P=0.015; 0.014; <0.0001; and<0.0001, respectively) while age groups, triggering trauma for thefirst bleeding, type of the first bleeding, history of previous trauma,the most frequent type of bleeding, age at diagnosis, and con-sumption of cryoprecipitate cannot. (P=0.985; 0.475; 0.342; 0.318;0.058; 0.477; and 0.547, respectively).Conclusion Age at first bleeding, frequency of bleeding, and fam-ily history can be used to predict classification of hemophilia A.
Co-Authors Agus Firmansyah Rina Rahardiani