People Live With HIV/AIDS (PLWHA) based on study in Malanu Public Health Center known that there are still around 20.2% of PLWHA who are actively taking ARV therapy while the rest of PLWHA are no longer actively taking ARV therapy. The purpose of this research to determine the relationship between family support and adherence to taking ARV in PLWHA at the Malanu Public Health Center. Method uses quantitative research with cross sectional approach. The research sample found 36 respondents of PLWHA who were recorded at the Malanu Public Health Center. The sampling technique used is accidental sampling. The research instrument used is a questionnaire and the statistical test used is the chi square test. The results of this study indicate that there is a correlation between family support and adherence to taking ARV in PLWHA at the Malanu Health Center in Sorong City with p-value of 0.000
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