Health literacy is a key determinant of chronic disease management, affecting treatment adherence, self-care behaviors, and health outcomes. This study systematically reviewed the role of health literacy in chronic disease management, analyzing existing literature from databases such as PubMed, Scopus, and Google Scholar. The findings reveal a significant correlation between high health literacy and improved disease control, medication adherence, and reduced complications. However, disparities in health literacy remain prevalent, particularly among lower socioeconomic groups and populations with limited healthcare access. Systemic barriers, including insufficient health education, digital health inequities, and policy gaps, hinder progress in improving health literacy. Addressing these challenges requires integrating patient-centered education programs, leveraging digital health technologies, and fostering community engagement. Policymakers must implement inclusive health literacy policies to bridge knowledge gaps and enhance healthcare accessibility. Future research should focus on evaluating long-term health literacy interventions and their impact on chronic disease outcomes. Strengthening health literacy initiatives is essential for reducing health disparities and optimizing patient well-being.
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