Jurnal Biologi Tropis
Vol. 25 No. 2 (2025): April-Juni

Genetic Variation Analysis of L1 gene HPV-16 using RFLP in Silico

Afionita, Santi (Unknown)
Putri, Dwi Hilda (Unknown)
Achyar, Afifatul (Unknown)
Yuniarti, Elsa (Unknown)

Article Info

Publish Date
23 Apr 2025

Abstract

Human papillomavirus (HPV) is one of the leading causes of cervical cancer, with the L1 gene playing an important role in vaccine development. This study aims to analyze the genetic variation of the L1 gene of HPV types 16, 18, 52, and 58 using the RFLP method in silico by utilizing restriction enzymes. The results showed that. The pattern of genetic conservation is more dominant in HPV 16 and 52 than other types, indicating the potential important role of the L1 gene in vaccine development. This study confirms the importance of analyzing genetic variation to understand HPV genetic diversity. These results may contribute to the development of more specific vaccines and molecular markers for HPV detection.

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Journal Info
Jurnal Biologi Tropis
Website

Abbrev

JBT

Publisher

Universitas Mataram

Subject

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology

Description

Jurnal Biologi Tropis (ISSN Cetak 1411-9587 dan ISSN Online 2549-7863) diterbitkan mulai tahun 2000 dengan frekuensi 2 kali setahun oleh Program Studi Pendidikan Biologi PMIPA FKIP Universitas Mataram, berisi hasil penelitian dan ulasan Ilmiah dalam bidang Biologi ...