Jurnal Pharmactive
Vol. 2 No. 2 (2023): Jurnal Pharmactive Oktober

Antibacterial Activity of 96% Ethanol Extract from Red Rice Bran (Oryza nivara) Against Escherichia coli: Uji Aktivitas Antibakteri Ekstrak Etanol 96% Bekatul Beras Merah (Oryza nivara) terhadap Escherichia coli

Ni Luh Gde Mona Monika (Unknown)
Ni Wayan Rika Kumara Dewi (Unknown)
Ni Putu Gita Puspita Sari (Unknown)



Article Info

Publish Date
30 Oct 2023

Abstract

Red rice bran is a by-product produced from rice milling in Jatiluwih village, Tabanan, Bali which has secondary metabolites that have the potential to inhibit bacterial activity. The purpose of this study was to determine the potential of 96% ethanol extract of red rice bran to inhibit bacterial growth Escherichia coli. The research method started with the extraction process by maceration method using 96% ethanol solvent. The viscous extract obtained was then subjected to phytochemical screening which showed the presence of compounds flavonoid, alkaloid, and tannin. Antibacterial activity test using disc diffusion method paper disk, measured by looking at the clear zone formed and analyzed using the mean test. The antibacterial activity test results of red rice bran extract at concentrations of 20% (8.63 mm) and 25% (9.93 mm) were categorized as moderate, concentration 30% (10.33 mm) was categorized as strong inhibition. Positive control in this study using chloramphenicol 250 mg which resulted in an inhibition zone of 21.42 mm in the strong inhibition zone category. Comparison of the antibacterial activity of the 96% ethanol extract of red rice bran showed significant difference with p value <0.05.

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Journal Info

Abbrev

jpharmactive

Publisher

Subject

Environmental Science Other

Description

Initially LPPM Institut Teknologi dan Kesehatan Bintang Persada published a journal that aimed to accommodate campus internal lecturers at Institut Teknologi dan Kesehatan Bintang Persada in publishing scientific papers. Because the lecturers who want to carry out publications come from various ...