Cermin Dunia Kedokteran
Vol 45 No 12 (2018): Interna

Diagnosis dan Tatalaksana Non-Cirrhotic Portal Hypertension

Dian Daniella (Fakultas Kedokteran Universitas Katolik Atma Jaya, Jakarta, Indonesia)
Michelle Octoviani Kristianto (Fakultas Kedokteran Universitas Katolik Atma Jaya, Jakarta, Indonesia)



Article Info

Publish Date
03 Dec 2018

Abstract

Non-cirrhotic portal hypertension (NCPH) merupakan hipertensi portal tanpa sirosis, terjadi pada 10% pasien hipertensi portal. Komplikasi paling sering NCPH adalah varises esofagus yang juga merupakan penyebab kematian terbanyak. Penyakit ini sulit didiagnosis karena prevalensi rendah dan manifestasi klinis beragam, umumnya varises esofagus, splenomegali, dan anemia. Pada pemeriksaan ultrasonografi dan biopsi hepar hasilnya normal. Terapi NCPH adalah beta-blocker untuk mengurangi tekanan portal, terapi endoskopik untuk mengatasi varises esofagus, dan operasi. Non-cirrhotic portal hypertension (NCPH) is a portal hypertension that occurs in the absence of cirrhosis, which occurs only in 10% portal hypertensive patients. The most frequent complication of NCPH is esophageal varices that is also the leading cause of death. Diagnosis is difficult because of low prevalence and multiple clinical manifestations, usually as esophageal varices, splenomegaly, and anemia, while ultrasonographic and liver biopsy are normal. Treatment is beta-blockers to reduce portal pressure, endoscopic therapy to overcome esophageal varices, and surgery

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Journal Info

Abbrev

cdk

Publisher

Subject

Health Professions

Description

Cermin Dunia Kedokteran (CDK) is a Medical Journal published since 1974 and affiliated with PT Kalbe Farma Tbk. CDK is intended to help accommodate scientific publications and help increase and disseminate knowledge related to the development of medical science, pharmacy, and public health. CDK ...