Cermin Dunia Kedokteran
Vol 45 No 7 (2018): Onkologi

Zika Virus and its Threads to Microcephaly

Dias Rima Sutiono (Indonesia International Institute for Life Sciences (i3L), Jakarta, Indonesia)
Cintya Pradnya Pratita (Indonesia International Institute for Life Sciences (i3L), Jakarta, Indonesia)



Article Info

Publish Date
02 Jul 2018

Abstract

The infection of ZIKV is through transplacental transmission. Polymerase Chain Reaction (PCR) detected the strains of ZIKV inside amniotic fluid only when in other fluids : serum and urine, revealed negative results. Microcephaly with numerous calcifications were discovered in the fetus of all cases. Ventriculomegaly and CNS structures anomalies were also discovered, though some structures such as subcortical nuclei of the brain and ascending dorsal columns of the spinal tract were well preserved.   Infeksi ZIKV melalui transmisi plasenta. Galur ZIKV dalam cairan ketuban dapat dideteksi menggunakan Polymerase Chain Reaction (PCR) hanya jika cairan lainnya, serum dan urin, negatif. Mikrosefali dengan kalsifikasi di semua kasus; lingkar kepala janin di bawah persentil kedua (34 cm). Ventrikulomegali dan struktur system saraf pusat abnormal, meskipun beberapa struktur seperti inti subkortikal otak dan jaras dorsalis medulla spinalis masih baik.

Copyrights © 2018






Journal Info

Abbrev

cdk

Publisher

Subject

Health Professions

Description

Cermin Dunia Kedokteran (CDK) is a Medical Journal published since 1974 and affiliated with PT Kalbe Farma Tbk. CDK is intended to help accommodate scientific publications and help increase and disseminate knowledge related to the development of medical science, pharmacy, and public health. CDK ...