MEDICA (International Medical Scientific Journal)
Vol. 6 No. 2 (2024): MEDICA (Internasional Medical Scientific Journal)

Impact of Sample Delay on Leukocyte and Platelet Parameters in Dengue Fever Patients: A Hematological Analysis

Utami, Luh Mitha Ari (Unknown)
Bekti, Heri Setiyo (Unknown)
Dhyanaputri, I Gusti Ayu Sri (Unknown)



Article Info

Publish Date
31 May 2024

Abstract

Background: The diagnosis of Dengue Fever (DF) involves physical examination, laboratory tests, and confirmation primarily through thrombocytopenia and leukocyte abnormalities. Laboratory procedures play a crucial role; however, delays in complete blood count (CBC) analysis may influence hematological parameters, potentially affecting diagnostic accuracy. Objective: To determine the effect of 2-hour and 4-hour delays in CBC testing on leukocyte and platelet counts in patients with Dengue Fever. Methods: This experimental study used a posttest-only control group design with purposive sampling. Blood samples from DF patients were divided into three groups: immediate testing, 2-hour delay, and 4-hour delay. Data were analyzed using the Shapiro-Wilk test followed by Multivariate Analysis of Variance (MANOVA). Results: The mean leukocyte and platelet counts in the immediate testing group were 4.86×10³/μL and 61.55×10³/μL, respectively. In the 2-hour delay group, leukocyte counts slightly decreased to 4.79×10³/μL and platelet counts increased to 65.77×10³/μL. In the 4-hour delay group, leukocyte counts increased to 4.85×10³/μL while platelet counts decreased to 64×10³/μL. MANOVA results (Sig. = 1.000) indicated no significant differences among the groups. Conclusion: Delays of 2 and 4 hours in CBC testing did not significantly affect leukocyte and platelet counts in Dengue Fever patients. These findings suggest that short-term delays in sample analysis may not compromise hematological results in DF diagnosis.

Copyrights © 2024






Journal Info

Abbrev

medica

Publisher

Subject

Chemistry Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary

Description

MEDICA (International Medical Scientific Journal), with registered number ISSN 2622-6596 (Print), 2622-660X (Online) is an Open Access and peer-reviewed journal presenting timely research on all aspects of health that other media have not published. Managed by the Borneo Scientific Publishing, ...