Journal of Biomedicine and Translational Research
Vol 11, No 1 (2025): April 2025

Genetic Counselling Empowers Parents of Children with Intellectual Disabilities : A Fragile X Syndrome Perspective

Amir, Mentari (Unknown)
Aulia, Siti Farhanah (Unknown)
Ranakusuma, Octaviani Indrasari (Unknown)
Faradz, Sultana MH (Unknown)



Article Info

Publish Date
30 Apr 2025

Abstract

Background: Intellectual disabilities (ID) profoundly affect individuals and their families, leading to financial strain, emotional distress, and limited access to healthcare and education. Fragile X Syndrome (FXS), the most common inherited cause of ID, remains largely underdiagnosed in Indonesia due to limited awareness and resources. Objective: This study aimed to assess the impact of genetic counselling on parental empowerment. Methods: This pre-experimental study employed a before and after counselling. A total of 238 parents of children with ID from four special schools in Jakarta participated. Data were collected using the Genetic Counselling Outcome Scale-24 (GCOS-24), which assesses empowerment. Purposive sampling was applied, and data were analysed using paired t-tests and one-way ANOVA. Results: The mean GCOS-24 score increased significantly from 106.79 (SD = 16.36) before counselling to 125.11 (SD = 15.42) after counselling (p < 0.001). Only 27.3% of parents were aware of genetic disorders, reflecting their limited baseline knowledge. A one-way ANOVA analysis showed a statistically significant difference in GCOS-24 score improvements based on parental education level (F=4.035, p=0.008) with parents with primary school education showing the greatest improvement compared to those with high school (p < 0.05). Conclusions: Genetic counselling significantly enhanced parent empowerment, as evidenced by increased GCOS-24 scores. These findings emphasize the importance of expanding genetic counselling services and educational initiatives in Indonesia to improve awareness and support for families managing ID.

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Journal Info

Abbrev

jbtr

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology

Description

Journal of Biomedicine and Translational Research (JBTR) is an open access, international peer-reviewed journal that considers articles on: clinical medicine, molecular medicine, tropical medicine, infectious diseases, cardiovascular medicine, molecular biology, genetics, immunology, microbiology, ...