<![CDATA[Monkeypox is a zoonotic disease that has spread to various countries, including Indonesia. It is transmitted through direct contact with skin lesions, respiratory droplets, or contaminated objects. Early and accurate detection is crucial to reduce the risk of transmission and improve treatment effectiveness. This study aims to detect monkeypox using a Convolutional Neural Network (CNN) with the ResNet-101 architecture. The pre-processing steps include normalization and resizing of images to 224×224 pixels. The model is trained using the Adam optimizer, categorical crossentropy loss function, and an adaptive learning rate reduction. Evaluation results show that the model achieved an accuracy of 94%, with a precision of 0.92, recall of 0.92, and an F1-score of 0.92. The model is capable of classifying images effectively, although some misclassifications still occur. This system is intended to function as an initial image-based screening tool, but its results should be confirmed through clinical diagnosis and laboratory testing to ensure accuracy.]]>
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