Pharmaceutical Journal of Indonesia
Vol. 10 No. 2 (2025)

Cost-Effectiveness Analysis of The Antibiotic Ampicillin and Cefuroxime for Bronchopneumonia Patients Toddlers at Secondary Hospital in Surabaya

Wardhani, Dewanti (Unknown)
Firdaus, Favian Rafif (Unknown)
Yunita, Nita (Unknown)
Abdul, Rahem (Unknown)



Article Info

Publish Date
30 Jun 2025

Abstract

Bronchopneumonia is an infectious disease in toddlers that produces high mortality, morbidity, and costs. The research aims to investigate the cost-effectiveness of ampicillin and cefuroxime for treating bronchopneumonia in toddlers. Data was collected retrospectively from medical records and hospital information systems between March 2023 and August 2023. The hospital-based trial was completed in October 2023. Stratified random sampling was employed to gather samples from those who met the inclusion criteria, which included using ampicillin or cefuroxime and having bronchopneumonia symptoms. Therapeutic success was determined by achieving a normal breathing rate within < 3 days, taking into account total direct medical expenses. The study discovered that the average direct medical cost for ampicillin patients is Rp. 2,792,875 ± 454.704, and for cefuroxime patients, Rp. 2.931.682 ± 908.964 per inpatient. The effectiveness of antibiotics showed that ampicillin (98%) surpassed cefuroxime (96%). Ampicillin's average cost-effectiveness ratio (ACER) is Rp. 28,499, which is less than cefuroxime's Rp. 30,538. The findings of calculating the incremental cost-effectiveness ratio (ICER) of ampicillin and cefuroxime are Rp. -69,404. Ampicillin has lower direct medical costs and higher effectiveness than cefuroxime, making it a more cost-effective therapy for bronchopneumonia in toddlers. Cost-effectiveness pharmacoeconomic studies are necessary to analyze therapy options

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Journal Info

Abbrev

pji

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Description

Pharmaceutical Journal of Indonesia (PJI) is an online journal which is published twice a year by Department of Pharmacy, Faculty of Medicine, Brawijaya University. The articles published in PJI cover the themes of Clinical and Community Pharmacy, Pharmaceutical Chemistry, Pharmaceutical Technology, ...