Sasambo Journal of Pharmacy
Vol. 6 No. 1 (2025): April

Qualitative and quantitative analysis of prednisone chemical content in rheumatic herbs in Magelang Region

Afifah, Riza Nur (Unknown)
Wardani, Arief Kusuma (Unknown)
Kusuma, Tiara Mega (Unknown)



Article Info

Publish Date
30 Apr 2025

Abstract

Currently, there is a phenomenon that shows that many herbs consumed by the public contain medicinal chemicals (BKO). This study aims to identify the presence of BKO prednisone in rheumatic herbs and its levels. This study took five types of samples of rheumatic herbs in Magelang area with different brands, namely samples of herbs A, B, C, D and E, which are available in capsule and powder form. Identification of prednisone in rheumatic herbs was carried out using thin layer chromatography (TLC) method with silica gel GF254 as stationary phase and ethyl acetate: chloroform mixture (4:1) as mobile phase. Quantitative analysis was performed using UV-Vis spectrophotometry with a maximum wavelength of 238.5 nm. The rf value of prednisone standard 0.42 was obtained and quantitative analysis showed that the prednisone content in sample B in the first replication was 3.22%, in the second replication was 2.18%, in the third replication was 2.23%.

Copyrights © 2025






Journal Info

Abbrev

sjp

Publisher

Subject

Health Professions Medicine & Pharmacology

Description

Sasambo Journal of Pharmacy (p-ISSN: 2723-2824; e-ISSN: 2723-2832) is a scientific journal publishing original articles research in pharmaceutical science. The Journal is managed by the Pharmacy Study Program, Mataram University. Sasambo Journal of Pharmacy receives manuscripts in both English and ...