Journal of Applied Pharmaceutical Research
Vol 5 No 2 (2017)

Bioanalytical method development and validation of bleomycin sulphate

Prashar, Yash (Unknown)
Rana, Harkaran Singh (Unknown)
Bais, Souravh (Unknown)

Article Info

Publish Date
29 Apr 2017

Abstract

Bleomycin is an anti-neoplastic drug that has recently been used for the treatment of vascular anomalies. An expedient method was developed for the determination of plasma bleomycin levels using ion-paired reversed phase high performance liquid chromatography (HPLC). The concentration was found to be proportional to the area and the response of the detector was determined to be linear over the range of 1-6 µg/ml for both Bleomycin A1 and Bleomycin B2. Recovery was approximately 100%. This method provides a simple and rapid way of determining the levels of bleomycin A2 and B2 in human and rat plasma

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Journal Info
Journal of Applied Pharmaceutical Research
Website

Abbrev

joapr

Publisher

Creative Pharma Assent

Subject

Medicine & Pharmacology

Description

Journal of Applied Pharmaceutical Research (JOAPR) is an official publication of Creative Pharma Assent (CPA). It is an open access, peer review online international journal. JOAPR is primarily focused on multiple discipline of pharmaceutical sciences (Pharmaceutics, Pharmaceutical Technology, ...