This study is motivated by the importance of developing multicultural literacy skills among elementary school students in responding to the cultural diversity of Indonesia. The aim of this research is to examine the effect of the Culturally Responsive Teaching (CRT) approach on students' multicultural literacy skills. The study employs an experimental method with a true experimental design. The population consists of 91 fifth-grade students at SD Negeri 141 Palembang. A sample of 45 students was selected and divided into an experimental class and a control class. The experimental class was taught using the Culturally Responsive Teaching approach, while the control class received conventional instruction. The data collection instrument was a multicultural literacy test consisting of 15 essay questions, developed based on indicators of multicultural literacy skills. The data analysis techniques included normality test, homogeneity test, and hypothesis testing using the independent sample t-test. The results of the study indicate that the Culturally Responsive Teaching approach has a significant effect on students’ multicultural literacy skills.
                        
                        
                        
                        
                            
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