Cermin Dunia Kedokteran
Vol 52 No 7 (2025): Kedokteran Umum

Perdarahan Perirenal Spontan pada Pasien dengan Sindrom Antifosfolipid: Laporan Kasus

Adipurnama, William (Unknown)
Oktaviani, Jacinda Risha (Unknown)
Singgih, Nicholas Andrian (Unknown)
Salim, Cecilia Noviyanti (Unknown)
Derry Wendians Suhanto (Unknown)
Manuputty, Egi Edward (Unknown)
Budiawan Atmadja (Unknown)



Article Info

Publish Date
07 Jul 2025

Abstract

Introduction: Spontaneous perirenal hemorrhage (SPH), also known as Wunderlich syndrome, is a rare condition that can potentially progress into life-threatening non-traumatic retroperitoneal hemorrhage. Common symptoms include acute flank or abdominal pain, a palpable flank mass, and fulminant hypovolemia, collectively referred to as Lenk’s triad, and diagnosis is typically established radiologically using a CT scan. Antiphospholipid syndrome (APS) - a rare, immune-mediated hypercoagulable disorder that occurs in only 5 cases per 100,000 people per year worldwide. It is immune-mediated, characterized by persistent antiphospholipid antibodies (APLA) that cause both arteries and venous thrombosis, and can present as peripheral arterial disease (PAD), acute arterial occlusion, and early atherosclerosis. Case : A 33-year-old woman with chronic kidney disease (CKD) presented with SPH and incidentally diagnosed with peripheral arterial disease (PAD) and APS. Conclusion : Conservative management was beneficial for SPH without the need for surgical intervention; however, antithrombotic therapy for PAD posed additional challenges before the patient was eventually discharged in improved condition for outpatient follow-up.

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Journal Info

Abbrev

cdk

Publisher

Subject

Health Professions

Description

Cermin Dunia Kedokteran (CDK) is a Medical Journal published since 1974 and affiliated with PT Kalbe Farma Tbk. CDK is intended to help accommodate scientific publications and help increase and disseminate knowledge related to the development of medical science, pharmacy, and public health. CDK ...