Journal of Applied Data Sciences
Vol 6, No 3: September 2025

A Hybrid CNN-Transformer Model with Quantum-Inspired Fourier Transform for Accurate Skin Disease Classification

S, Aasha Nandhini (Unknown)
Manoj, R. Karthick (Unknown)
Batumalay, M. (Unknown)



Article Info

Publish Date
12 Jul 2025

Abstract

Skin disease classification is a complex task that requires robust feature extraction, efficient classification, and interpretability. Artificial intelligence-based technologies offer effective solutions for developing a framework for skin disease classification while ensuring explainability for healthcare professionals. This study proposes a novel Hybrid Transformer model comprising of Convolutional Neural Network (CNN) architecture infused with a Quantum-Inspired Fourier Transform (QIFT) to enhance classification accuracy. QIFT is incorporated to emphasize frequency-domain information alongside the spatial features captured by CNNs, potentially improving feature representation and model generalization. For demonstration, a dataset containing four different classes of dermatological images is used. Data augmentation techniques and adaptive learning rate scheduling are employed to optimize the dataset. A weighted cross-entropy loss function is used to address class imbalances in the dataset. In this research, explainability is implemented using a standard attribution technique like Integrated Gradients providing insights into model decision-making, and enhancing trust in medical applications. Performance evaluation involves validating the proposed framework using metrics such as confusion matrix analysis, classification reports, and training-validation curves. Experimental results demonstrate a high classification accuracy of 92.5% across skin disease categories. The findings indicate that integrating QIFT and CNN-based feature extraction with transformer-driven attention mechanisms enhances skin disease classification performance while ensuring interpretability as process innovation.

Copyrights © 2025






Journal Info

Abbrev

JADS

Publisher

Subject

Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management

Description

One of the current hot topics in science is data: how can datasets be used in scientific and scholarly research in a more reliable, citable and accountable way? Data is of paramount importance to scientific progress, yet most research data remains private. Enhancing the transparency of the processes ...