Jurnal Kedokteran Meditek
Vol 31 No 4 (2025): JULI

Analysis of Intra-Articular Injection of Triamcinolone Acetonide on Changes in The Quality of Life of Patients With Knee Osteoarthritis

Lestari, Dewi (Unknown)
Widowati, Galuh (Unknown)



Article Info

Publish Date
15 Jul 2025

Abstract

Introduction: Knee osteoarthritis is the most common articular disease in developed countries that caused chronic disability and reduction of the quality of life in the elderly. Intra-articular (IA) injections are selected if other conservative therapies are ineffective. Purpose: This study aimed to measure the effect of IA injection of triamcinolone acetonide on the quality of life in knee osteoarthritis’s patients. Methods: This observational research was conducted in three steps: filling out questionnaires by patients, interviewing patients, and retrieving patients' data from medical records. The patients' quality of life scores measure before and 4 weeks after therapy, using the AIMS2-SF score, VAS EQ-5D-5L, and Indonesian EQ-5D-5L. The result will be declared statistically significant if p<0.05. Results: No statistically significant difference found in AIMS2-SF scores (p> 0.05) for Symptoms, Social, Occupational domains, and in VAS EQ-5D-5L (p> 0.05). A significant difference was found in AIMS2-SF scores for Physical, Emotional domains and in the EQ-5D-5l Score. Multivariate analysis showed that patients' characteristics and knee osteoarthritis disease did not affect the AIMS2-SF, EQ-5D-5L, and VAS score. Conclusion: IA injection of triamcinolone acetonide has a potential effect to increase the number of domains in the patient's quality of life after 4 weeks of therapy.

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Journal Info

Abbrev

Meditek

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

Description

Jurnal Kedokteran MEDITEK merupakan jurnal ilmiah yang mempublikasikan artikel-artikel dalam lingkup bidang kedokteran dan biomedik secara open access. Proses publikasi artikel melalui proses penelaahan oleh pakar sebidang (peer-review) secara double-blind. Jurnal Kedokteran Meditek berafiliasi pada ...