<![CDATA[Background: Nanotechnology has emerged as a transformative discipline, enabling groundbreaking advancements in biomedical engineering. The integration of nanoscale materials and techniques has revolutionized diagnostics, therapeutics, and regenerative medicine, offering unprecedented precision and efficiency. Aims: This paper examines the pivotal role of nanotechnology in advancing biomedical engineering applications, focusing on drug delivery systems, diagnostic tools, and tissue engineering innovations. Research Method: A comprehensive review methodology was employed, analyzing peer-reviewed articles, experimental studies, and clinical trials from reputable scientific databases. The analysis emphasized the design, synthesis, and implementation of nanomaterials and their impact on biomedical outcomes. Results and Conclusion: Nanotechnology significantly enhances drug delivery systems by enabling targeted therapy with minimized side effects. In diagnostics, nanosensors and imaging agents improve early disease detection. Tissue engineering has benefited from nanomaterials that mimic natural extracellular matrices, promoting cell proliferation and differentiation. Challenges such as biocompatibility, scalability, and regulatory issues persist but are gradually being addressed through interdisciplinary collaboration. Contribution: This study consolidates current knowledge on nanotechnology’s contributions to biomedical engineering and identifies future directions for research, emphasizing the need for ethical and sustainable practices in nanotechnology applications. ]]>
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