Medical and Health Journal
Vol 5 No 1 (2025): August

Antioxidant and Anti-Inflammatory Activities of Kecombrang (Etlingera elatior) Extracts: A Systematic Literature Review

Pribadi, Fajar Wahyu (Unknown)
Robbani, Muhammad Izzulfahmi (Unknown)
Salsabila, Chasna (Unknown)
Alifia, Carrissa (Unknown)
Kanti, Kanaya Adhira (Unknown)
Akbar, Vania Nafiisa (Unknown)
Andini, Sofia Dewi (Unknown)
Firdaus, Naila Asy Syifa (Unknown)
Arrasyi, Alifah Putri Nur (Unknown)
Adiwijaya, Kharisma (Unknown)



Article Info

Publish Date
02 Aug 2025

Abstract

Kecombrang (Etlingera elatior) is a plant commonly used in traditional medicine and as a food seasoning by the Indonesian community. It contains various secondary metabolites such as saponins, tannins, alkaloids, steroids, flavonoids, and phenolic compounds, which are distributed from its rhizomes to its flowers. This literature review aims to provide a deeper understanding of the active compounds in kecombrang and their potential health benefits for humans. The study was conducted as a literature review using the PRISMA method, with data sources from four major databases: ScienceDirect, PubMed, Scopus, and Google Scholar. Findings from several studies involving rats as test subjects indicate that the active compounds in kecombrang exhibit antioxidant effects that protect cells from oxidative damage. Additionally, kecombrang extract demonstrates anti-inflammatory activity by directly inhibiting the enzymes COX and lipoxygenase, thereby reducing the biosynthesis of prostaglandins and leukotrienes.

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Journal Info

Abbrev

mhj

Publisher

Subject

Medicine & Pharmacology

Description

Medical and Health Journal (EISSN. 2807-3541) is containing various articles/ manuscripts in the forms of research article, systematic reviews, case reports in the field of medicine focusing on basic medicine, clinical medicine, biomedical sciences, medical biotechnology, and public health. This ...