Free radicals accelerate skin aging and cellular damage. Kersen leaves (Muntingia calabura L.) are known to contain flavonoids, saponins, and tannins with antioxidant potential. This study aimed to formulate a facial serum using ethanolic extract of kersen leaves and evaluate its physical properties and antioxidant activity. The extract was obtained via maceration using 96% ethanol and formulated into three concentrations: 5%, 10%, and 15%. Physical evaluations included organoleptic properties, homogeneity, pH, spreadability, viscosity, and irritation tests. Antioxidant activity was assessed using the DPPH method, with IC₅₀ values as indicators. All formulations met the physical quality standards. The 5% extract formula exhibited the highest antioxidant activity with an IC₅₀ value of 72.22 μg/mL, classified as active. Irritation tests confirmed that all formulations were safe for topical use. These findings support the potential of kersen leaf extract as a natural antioxidant ingredient in cosmetic formulations.
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