BIOLINK (Jurnal Biologi Lingkungan, Industri, Kesehatan)
Vol. 12 No. 1 (2025): Biolink August

ISOLATION AND SELECTION OF ENDOPHYTE FUNGI FROM THE ANDALIMAN PLANT (Zanthoxylum acanthopodium DC) AS ANTIFUNGAL

Idramsa, Idramsa (Unknown)
Ayu, Nur (Unknown)



Article Info

Publish Date
06 Aug 2025

Abstract

Dermatophytosis (Ringworm) is a disease caused by dermatophyte fungal infection that attacks the epidermis (keratin) tissue such as skin, nails and hair in humans. Antibiotics as a drug for fungal infections that are often used by the public are known to have side effects, so that alternative drugs are needed that are relatively safe to use. Endophytic microbes found in plants are known to be an alternative natural medicine that does not have side effects, because they contain bioactive compounds. This study aims to isolate, select and identify endophytic fungi in andaliman plants (Zanthoxylum acanthopodium DC) and determine their potential as antifungals against dermatophytosis fungi. Exploration methods were used, molecular analysis using marker genes Internal Transcribed Spacer (ITS) and antifungal activity tests (Dual culture) against Tricophyton rubrum and Tricophyton mentagrophytes as pathogenic test fungi. The results showed that endophytic fungus from the species Diaporthe phaseolorum (Isolate EF128). has very strong antifungal activity against the test fungus Tricophyton rubrum and is strong against Tricophyton mentagrophytes (isolate IJE D3). so it has the potential as an antifungal.

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Journal Info

Abbrev

biolink

Publisher

Subject

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology

Description

Biolink focuses on the publication of the results of scientific research related to fields. This article is published in the internal and external academic community of the University of Medan Area (UMA) especially in the field of Biology. Biolink publishes scientific articles in the scope of ...