This study aimed to investigate the effect of scaffolding guidance on improving science process skills of 10th grade students in green chemistry learning. The research employed a mixed-method approach with a quasi-experimental time series design involving 36 students at SMA Negeri 2 Muaro Jambi. Scaffolding techniques were implemented progressively through four stages: explaining, prompting, cueing, and questioning across four meetings. Data were collected through observation sheets, pretest-posttest assessments, and interviews. Results showed significant improvement in students' science process skills, particularly in measuring and communicating results. Statistical analysis using dependent t-tests revealed significant differences (p < 0.05) across all meetings. Effect size calculations showed large effects (Cohen's d > 0.8) for all scaffolding techniques. The cueing technique demonstrated highest effectiveness for measuring skills (t = -10.023), while questioning was most effective for communication skills (t = -9.791). This research contributes to science education by demonstrating that progressive scaffolding guidance can effectively enhance students' science process skills in chemistry learning contexts.
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