By the end of 2023, global HIV prevalence reached 5‰ with a Case Fatality Rate (CFR) of 16‰. In Indonesia, prevalence stands at 2‰, while incidence has increased from 13 per 100,000 population in 2021 to 21 per 100,000 in 2023, with a CFR of 7‰. In Medan City, HIV incidence reached 70 per 1,000 population. Padang Bulan Community Health Center (Puskesmas) is a health facility in Medan providing voluntary counseling and testing (VCT) services. This study aims to analyze the relationship between sociodemographic and HIV incidence at the VCT Clinic of Padang Bulan Community Health Center Medan in 2025. This study employs an analytic observational design with a cross-sectional approach, involving 85 samples by purposive sampling. Univariate data were analyzed descriptively and bivariate data were analyzed by chi square test with 95 percent confidence level (α=0.05). Results showed that 75.3% of respondents at the VCT Clinic of Padang Bulan Medan Health Center in 2025 were diagnosed HIV-positive. There was an association between gender (p < 0.05), marital status (p < 0.05), education level (p < 0.05), income (p < 0.05), STI history (p < 0.05), place of residence (p < 0.05), and mode of sexual intercourse (p < 0.05) with HIV incidence. Meanwhile, age (p > 0.05), ethnicity (p > 0.05), occupation (p > 0.05), and regional origin (p > 0.05) has no significant association with HIV incidence. Individuals with HIV should adhere to antiretroviral treatment and adopt a healthy lifestyle to improve quality of life and prevent transmission.
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