Jambura Journal of Chemistry
Vol 6, No 2 (2024): August

Comparative Studies on Proximate and In Vitro Anti-Inflammatory Activities Turmeric Methanol Extract In Albino Wistar Rats

Adio, Waheed Sakariyau (Unknown)
Salawudeen, Wahab (Unknown)
Adesola, Ridwan Olamilekan (Unknown)
Adisa, Azeez Soliu (Unknown)
Obunadike, Chizoba Victory (Unknown)



Article Info

Publish Date
11 Aug 2024

Abstract

All throughout the world, turmeric has attracted the interest of scientists and medical specialists. The goal of this study was to pinpoint turmeric methanol extract's immediate proximate and anti-inflammatory activities. A spectrophotometric approach was used to choose the phytochemical screens (both qualitative and quantitative). The recent approach (standard method) was used to research the anti-inflammatory effects and proximate components of turmeric. The qualitative phytochemical screening revealed a substantial amount of turbid alkaloid (++) but no steroid (-). Phenol (151.34±1.01 mg/100g) had the highest concentration (5.83%), while flavonoid (22.30±0.62 mg/100g) had the lowest (5.83%), according to the quantitative screening. The anti-inflammatory activity of the turmeric methanol extract in the treated groups (150, 300, and 600 mg/kg body weight) and the positive control group demonstrated a valuable value (inhibitory values). Paw thickness was also significantly different (reduced) between the 600 mg/kg and positive control groups promising anti-inflammatory effects. These findings demonstrated that inflammation can be treated using turmeric's anti-inflammatory and adjuvant capabilities.

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Journal Info

Abbrev

jjc

Publisher

Subject

Chemistry

Description

Jambura Journal of Chemistry is peer-reviewed and open access journal published by Chemistry Depertment, Faculty Mathematic and Natural Science. Jam.J.Chem that publishes original research articles, review articles, as well as short communication in all areas of chemistry including applied ...