The Avicenna Medical Journal
Vol. 4 No. 2 (2023): The Avicenna Medical Journal

Age of children contributes to potential drug interaction at nine primary health cares

Sari, Flori R. (Unknown)



Article Info

Publish Date
01 Nov 2023

Abstract

Introduction: Adverse drug reaction including drug interaction should be prevented early in children’s patients since children are vulnerable subjects due to their biological development process. Our study aimed to identify the potential drug interaction in children’s patients from nine primary health cares (PHC) at Tangerang.Methods: This study was done with an analytical cross-sectional approach at nine PHC. All children patients from age 1 to 18 years old were recruited for two weeks study. All prescriptions were analyzed and categorized for potential drug interactions.Results: We identified 19 mild and moderate but not serious potential drug interactions from 791 prescriptions (2%). The most common mild potential drug interaction is paracetamol and domperidone as well as mefenamic acid and dexamethasone for moderate potential drug interaction. Number of drugs and gender did not significantly correlate to potential drug interactions, but age did (p=0.04).Discussion: We identified that age correlated significantly to potential drug interactions. In brief, the older the patients, the higher the possibility for the drug interactions, thus physicians should be more aware in prescribing drugs to older children’s patients.

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Journal Info

Abbrev

amedj

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Description

The Avicenna Medical Journal, the official journal of Faculty of Medicine Universitas Islam Negeri Syarif Hidayatullah Jakarta, presents multidisciplinary scientific papers which describe innovative research spanning the entire spectrum of medical aspects both basic science and clinical aspects. It ...