Jurnal Penelitian Farmasi dan Herbal
Vol 8 No 1 (2025): Jurnal Penelitian Farmasi dan Herbal

FORMULASI DAN UJI AKTIVITAS SEDIAAN GEL ANTIACNE EKSTRAK ETANOL DAGING KURMA (Pheonix dactylifera L.) TERHADAP BAKTERI Propionibacterium acnes & Pseudomonas aeruginosa

Marbun, Nova rianti (Unknown)
Br Sembiring, Tio Ranti Sari (Unknown)



Article Info

Publish Date
03 Nov 2025

Abstract

Acne (acne vulgaris) is a skin inflammation caused by the overgrowth of bacteria such as Propionibacterium acnes and Pseudomonas aeruginosa. This study aims to formulate a gel preparation containing ethanol extract of date flesh and evaluate its antibacterial activity. The extract was obtained via maceration using 70% ethanol. The gel was formulated in three extract concentrations: 10%, 20%, and 30%. Physical evaluations of the gel included organoleptic properties, homogeneity, pH, spreadability, and adhesiveness, while antibacterial activity was tested using the disk diffusion method. The results showed that the 30% concentration provided the largest inhibition zone against both test bacteria. Physical evaluations confirmed that the gel preparation met the criteria for a stable topical product. It can be concluded that the ethanol extract of date flesh can be effectively formulated into an antibacterial gel preparation and has potential as a natural antiacne product.

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Journal Info

Abbrev

JPFH

Publisher

Subject

Medicine & Pharmacology

Description

Aims and Scope The Pharmaceutical & Herb Research Journal is a scientific journal published by Institut Kesehatan Deli Husada which publishes research journals in the field of pharmacy. Indonesia has a lot of natural resources that have the potential to have pharmacological effects. This journal is ...