Mikailalsys Journal of Mathematics and Statistics
Vol 3 No 3 (2025): Mikailalsys Journal of Mathematics and Statistics

Modelling Measles Reoccurrence in Vaccinated Infants

Adeboye, O. A. (Unknown)
Adewale, S. O. (Unknown)
Odebiyi, O. A. (Unknown)
Oladejo, J. K. (Unknown)



Article Info

Publish Date
03 Jul 2025

Abstract

Measles is a highly contagious viral disease caused by the morbillivirus, marked by symptoms including fever, cough, runny nose, conjunctivitis, and a characteristic widespread rash. In severe cases, especially among young children and pregnant women, it can lead to complications such as ear infections, pneumonia, encephalitis, and death. This study develops a six-compartment deterministic mathematical model, expressed as a system of ordinary differential equations, to investigate the transmission dynamics of measles in human populations. The model was demonstrated to be both mathematically and epidemiologically well-posed. The basic reproduction number (R₀) was derived, and the stability analysis of the disease-free equilibrium showed it to be locally and globally asymptotically stable when R₀ < 1, and unstable when R₀ > 1. Sensitivity analysis using normalized forward sensitivity indices revealed the impact of various parameters on R₀. Specifically, parameters with negative indices, such as the vaccination rate and treatment rate reduce R₀ when increased, while those with positive indices, such as the effective contact rate increase R₀ when increased. These findings underscore the importance of increasing vaccination coverage, enhancing treatment efforts, and isolating infected individuals to control and prevent measles outbreaks. The model provides a theoretical framework for designing effective public health strategies to minimize the disease burden in the population.

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Journal Info

Abbrev

MJMS

Publisher

Subject

Engineering Mathematics Mechanical Engineering

Description

The journal contains scientific articles covering topics such as mathematical theory, statistical methods, the application of mathematics in various disciplines, and statistical data analysis. The primary objective of this journal is to promote a better understanding of mathematical and statistical ...