Viva Medika: Jurnal Kesehatan, Kebidanan dan Keperawatan
Vol 17 No 2 (2024)

Activity Test of 96% Ethanol Extract of Water Guava Leaf (Syzygium aqueum) on LDL and HDL Values with Propylthiouracil Induction in Rats

Setianingsih, Siti (Unknown)
Sunarti (Unknown)
Muhammad Maulana (Unknown)



Article Info

Publish Date
16 Aug 2024

Abstract

One of the plants that can be thought to have antihyperlipidemic potential is water guava leaves (Syzygium aqueum) because they contain chemical compounds, one of which is flavonoids. The aim of this research is to determine the activity of 96% ethanol extract of water guava leaves (EEDJA) as an antihyperlipidemic agent. Male Wistar rats were induced using propylthiouracil (PTU) for 2 weeks (14 days). Hyperlipidemic mice were divided into 5 test groups, CMC-Na group, simvastatin group, EEDJA group (100, 200 and 400) mg/BW. The solution was given to mice routinely once a day for 2 weeks (14 days) orally. The results of the study showed that there were differences before and after administration of EEDJA (100, 200 and 400) mg/BW in LDL and HDL levels with a significance value of 0.000 (<0.005). The conclusion from this study is that EEDJA has potential as an antihyperlipidemic agent in male white Wistar rats

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Journal Info

Abbrev

VM

Publisher

Subject

Health Professions Medicine & Pharmacology Nursing Public Health

Description

Viva Medika Is a journal that publishes articles or research results relating to health, nursing and midwifery issues. Viva Medika is published by Harapan Bangsa University twice a year (September and February). The mission of the Journal of Viva Medika is to disseminate and discuss scientific ...