Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan
Vol 10 No 2 (2025): Jurnal Ilmiah Ibnu Sina

COST UTILITY ANALYSIS PADA PASIEN DIABETES MELLITUS TIPE 2: INTEGRASI GULA DARAH, KOMORBIDITAS, BIAYA DAN KUALITAS HIDUP DALAM PENGAMBILAN KEPUTUSAN KLINIS

Ilahi, Fitrah Shafran (Unknown)
Nordin (Unknown)
Faqih, Muhammad (Unknown)
Yumassik, Abdul Mahmud (Unknown)
Mellyani H.S, Ananda (Unknown)



Article Info

Publish Date
31 Oct 2025

Abstract

Type 2 Diabetes Mellitus (T2DM) is one of the most prevalent chronic diseases in Indonesia and imposes a significant burden on healthcare costs. This study aimed to perform a Cost Utility Analysis (CUA) among T2DM patients by integrating blood glucose levels, comorbidities, direct medical costs, and quality of life. The research applied a cross-sectional design with prospective data collection using a convenience sampling technique. Quality of life was measured using the EQ-5D-5L questionnaire, while blood glucose levels, comorbidities, and direct medical costs were obtained from hospital medical records. Data analysis included descriptive statistics, Chi-Square tests, Logistic Regression analysis, and calculation of the utility index. The results showed that 38% of patients had good quality of life and 62% had poor quality of life, with an average utility index score of 0.5175. Random blood glucose levels of ≥200 mg/dL were found in 56% of respondents, while 44% had levels <200 mg/dL. Comorbidities were present in 52% of patients, while 48% had none. The median direct medical cost was IDR 425,500, with 62% categorized as high-cost and 38% as low-cost. Bivariate analysis revealed significant relationships between comorbidities, blood glucose levels, and direct medical costs with quality of life (p < 0.05). However, multivariate analysis showed that only blood glucose levels remained significant (p = 0.006). In conclusion, the overall quality of life of T2DM patients was generally poor, and blood glucose control was identified as the most influential independent factor affecting quality of life.

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Journal Info

Abbrev

JIIS

Publisher

Subject

Medicine & Pharmacology

Description

Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan is a broad-based primary journal covering all branches of pharmacy and its sub-disciplines that contains complete research articles, short communication and review articles. JIIS is a forum for the publication of quality and original works ...