Tolvaptan untuk Hiponatremia Euvolemik dan Hipervolemik: Tinjauan Narasi

Judian, Terence
Alexsander, Samuel

Cermin Dunia Kedokteran
Vol 51 No 12 (2024): Kedokteran Umum

Hyponatremia is an electrolyte imbalance disorder commonly found in clinical practice. Hyponatremia is associated with significant mortality and morbidity. Tolvaptan is an orally administered V2 receptor antagonist drug capable of aquaresis without excreting electrolytes, thus increasing plasma sodium concentration. Results from clinical trials showed tolvaptan to be a relatively safe and effective treatment in euvolemia and hypervolemia hyponatremia.