Benzena Pharmaceutical Scientific Journal
Vol 4 No 01 (2025): BENZENA PHARMACEUTICAL SCIENTIFIC JOURNAL

POTENSI ANTIOKSIDAN REBUSAN DAN SEDUHAN TEMU MANGGA (Curcuma mangga) DENGAN METODE DPPH

Halimah, Nur (Unknown)
Sa'ad, Muhammad (Unknown)



Article Info

Publish Date
18 Jul 2025

Abstract

Background : Free radicals are unstable molecules that cause oxidative stress and various chronic diseases. Antioxidant compounds can play a role in neutralizing free radicals. Plants as natural ingredients of traditional medicine contain secondary metabolite compounds that act as antioxidants. One of the plants used as an antioxidant is temu mangga (Curcuma mangga). The use of natural ingredients as medicine by the people in Indonesia mostly uses the boiling and steeping methods. Objective : This study aims to determine the antioxidant activity of boiled and brewed temu mangga rhizome (Curcuma mangga) compared to quercetin. And to determine the content of secondary metabolites that are responsible for antioxidant activity. Method : Phytochemical screening using color reagents to determine the content of secondary metabolites including: alkaloids, tannins, saponins, and flavonoids. Antioxidant activity was measured using the DPPH method using the parameter of the Inhibitory Concentration 50% (IC50) value with quercetin as a positive control. Result : The results showed that both methods have secondary metabolite compounds that are responsible for antioxidant activity, namely: alkaloids, tannins, saponins, and flavonoids. Both methods showed very strong antioxidant activity, with IC50 quercetin, boiling and brewing method respectively of 5.62 ppm; 5.75 ppm; and 5.53 ppm. The brewing method was slightly more effective, possibly because the temperature used was lower, thus maintaining the stability of thermolabile antioxidant compounds such as flavonoids. Conclusion : Extraction method has significant effect on antioxidant activity. The brewing method can be a more optimal traditional method to maintain antioxidant properties of Curcuma mangga.

Copyrights © 2025






Journal Info

Abbrev

benzena

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Immunology & microbiology Medicine & Pharmacology Public Health

Description

Benzena Pharmaceutical Scientific Journal adalah jurnal peer-review yang diterbitkan dua kali setahun (Juni dan Desember) oleh Fakultas Farmasi Universitas Pekalongan. Ini tersedia online sebagai sumber akses terbuka dan juga dalam bentuk cetak. Pernyataan ini memperjelas perilaku etis semua pihak ...