Jurnal Otomasi Kontrol dan Instrumentasi
Vol 17 No 2 (2025): Jurnal Otomasi Kontrol dan Instrumentasi

Pengembangan Perangkat Surface Plasmon Resonance (SPR) sebagai Transduser Biosensor

Fadli Hastito (Institut Teknologi Sumatera, 35365, Lampung, Indonesia)
Endang Juliastuti (Institut Teknologi Bandung, 40132, Bandung, Indonesia)
Brian Yuliarto (Institut Teknologi Bandung, 40132, Bandung, Indonesia)



Article Info

Publish Date
18 Oct 2025

Abstract

This study developed a simple and cost-effective laboratory-scale Surface Plasmon Resonance (SPR) device called β SPR. SPR is a sensitive, real-time, and non-labeling technique widely used to detect the concentration and quality of solutions. However, the very high price of commercial SPR devices is a barrier, so a portable and affordable version was developed. The β SPR device uses a Kretschmann configuration with a 670 nm laser, a polarizer, and a modified Porro BA4010 prism for a simpler and more efficient optical configuration. A thin gold film (~50 nm) is placed on the prism using immersion oil, and the test solution is flowed through a flow cell. The laser is fired at a 90° angle to induce p-polarized waves that trigger surface plasmon resonance. This phenomenon decreases the light reflectance, forming a dip curve used for analysis. The device was tested using glucose solution (0.05–0.27 M) and compared with a commercial SPR device (α SPR). The results show a shift in the angle with increasing concentration. The highest error was 6.53% at 0.05 M, and the lowest was 0.94% at 0.27 M. The β SPR sensitivity was recorded at 4.41⁰/M, showing promising performance for cost-effective biosensor applications.

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Journal Info

Abbrev

joki

Publisher

Subject

Chemical Engineering, Chemistry & Bioengineering Control & Systems Engineering Engineering Industrial & Manufacturing Engineering

Description

Jurnal Otomasi Kontrol dan Instrumentasi adalah jurnal ilmiah yang diterbitkan oleh Pusat Teknologi Instrumentasi dan Otomasi (PTIO), Institut Teknologi Bandung setahun dua kali (April - Oktober) untuk menyebarluaskan hasil-hasil penelitian dengan fokus dalam bidang otomasi, kontrol, dan ...