Foodborne disease is one of the disease burdens because it can lead to disability and mortality, particularly in children. Hepatitis A and typhoid are the primary causes of foodborne diseases in developing countries. Although the majority will recover, children with hepatitis A can be a source of transmission. Meanwhile, in addition to endemicity in Indonesia, antibiotic resistance to typhoid infections is rising. Vaccination is considered an economic measure to suppress the incidence and transmission of disease, as well as prevent outbreaks. To achieve the effectiveness and efficiency of vaccination, it is essential for the general practitioner to have a comprehensive understanding of the preparations, methods of use, storage, precautions, contraindications, and potential adverse effects of the vaccine. In addition, increased public awareness of the importance of vaccination and the implementation of good food hygiene are factors that support the success of foodborne disease prevention. Public education efforts through health facilities and schools need to be strengthened to expand childhood immunization coverage. Thus, it is hoped that the incidence of hepatitis A and typhoid can be significantly reduced, in line with national and global health program targets to reduce morbidity and mortality rates from vaccine-preventable diseases.
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