The integration of science and religious values in madrasah education often remains dichotomous and lacks deep epistemological unity. This study aims to describe the implementation of Biotheistic-based Biology learning and to reveal the essence of students' spiritual experiences at MA YPI Cikoneng, Bandung Regency. This research employed a qualitative method with a phenomenological approach. Data were collected through in-depth interviews, participatory observation, and documentation studies involving 10 purposively selected key participants. The results indicate that: (1) The implementation of Biotheistic learning is structured through the 'Webbed-Theistic' planning model and the execution of 'Scientific-Spiritual Inquiry,' integrating qauliyah and kauniyah verses; (2) Phenomenologically, students experience a paradigm shift where biological phenomena are viewed not merely as material mechanisms but as theophanies (manifestations) of God's greatness; (3) The essence of students' spiritual experience evolves from cognitive understanding to a sense of awe, culminating in a consciousness of servitude (being). This study concludes that the Biotheistic approach effectively transforms Biology learning into a means of ma'rifatullah (knowing God) that enhances students' spiritual awareness, despite constraints regarding time allocation.
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