JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA
Vol. 3 No. 2 (2016): JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA

Simultaneous Determination Of Sodium Benzoate And Sodium Cyclamate In Soft Drink Using High Performance Liquid Chromatography

Ariya Wijaya Putra (Unknown)
Asri Darmawati (Faculty of Pharmacy, Universitas Airlangga, Surabaya, Indonesia)
Juniar Mochtar (Unknown)



Article Info

Publish Date
09 Apr 2018

Abstract

Background: Sodium benzoate and sodium cyclamate are foods additives generally used as preservative and artificial sweeteners, respectively. Monitoring of sodium benzoate and sodium cyclamate need appropriate analytical method. Objective: The main objective of this study was to gain the optimum conditions for simultaneous determination of sodium benzoate and sodium cyclamate in soft drink by High Performance Liquid Chromatography. Methods: Measurement of the additives was performed in ยต-Bondapak RP18 column using methanol:phosphate buffer of pH 4 (42:58) as mobile phase with flow rate of 1 mL/minute. Results: It has shown that correlation coefficients (r) of sodium benzoate and sodium cyclamate was 0.9997 and 0.9991 respectively. Recoveries of the two analyst were acceptable. Conclusions: Five out of nine samples tested contained sodium cyclamate higher than the recommended concentration. All sodium benzoate containing samples were within the recommended concentration.

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Journal Info

Abbrev

JFIKI

Publisher

Subject

Chemistry Education Health Professions Medicine & Pharmacology Other

Description

Jurnal ini adalah jurnal peer-review nasional, yang diterbitkan dua kali dalam membahas tentang topik-topik hasil penelitian di bidang pelayanan dan praktik kefarmasian, konsultasi masyarakat, teknologi kefarmasian serta disiplin ilmu kesehatan yang terkait dengan erat. Jurnal ini memfokuskan pada ...