<![CDATA[Introduction: Periodontitis is a complex, multifactorial inflammatory disease of tooth-supporting tissues that can impair quality of life if left untreated. Therefore, treatment that can improve good clinical outcomes and last for a long time is needed. This case report aims to present the periodontal regenerative therapy of a patient with stage 3 grade B periodontitis using platelet-rich fibrin (PRF) combined with bovine bone graft and pericardium membrane. Case report: A 36-year-old female patient presented for treatment of her lower anterior teeth. She complained of gum bleeding, tooth mobility and discomfort when chewing food for one year. Clinical examinations showed deep periodontal pockets and alveolar bone loss up to half the length of the root of teeth 31 and 41. After the initial phase treatment, which comprises scaling and root planning, teeth contact point repairment, extra coronal fiber splint installation and occlusal adjustment are performed. The surgical phase treatment of regenerative therapy is then performed using PRF combined with bovine bone graft and pericardium membrane. Conclusion: Regenerative periodontal treatment using platelet-rich fibrin (PRF) combined with bovine bone graft and pericardium membrane is proven to improve clinical outcomes in pocket probing depth successful (PD) reduction, gain of clinical attachment level (CAL) and alveolar bone regeneration.]]>
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