Biomedical Research and Theory Letters
Vol. 1 No. 2 (2025): Biomedical Research and Theory Letters

Symptom-Based Management of Chronic Gastroesophageal Reflux Disease in a Young Adult: A Holistic Therapeutic Approach

Leokrisnha, Rhomy (Unknown)
Anggunan (Unknown)
Ijlal, M Raihan Raid (Unknown)
Nisa, Maisa Aqila Fazilatun (Unknown)
Hr, Marisha Alsahda (Unknown)
Regar, Mely Shanrina Br (Unknown)
Putri, Mentari Kusuma (Unknown)



Article Info

Publish Date
30 Oct 2025

Abstract

Gastroesophageal Reflux Disease (GERD) is a chronic gastrointestinal disorder resulting from the retrograde movement of gastric contents into the esophagus, often due to lower esophageal sphincter dysfunction. It is characterized by hallmark symptoms such as heartburn, regurgitation, epigastric pain, and may also present with extra-esophageal manifestations including chronic cough, hoarseness, or dental erosion. GERD significantly affects quality of life and, if left untreated, may lead to complications such as esophagitis, strictures, or Barrett’s esophagus. This case report presents a 21-year-old female with a history of recurrent GERD symptoms since childhood. She presented with complaints of persistent epigastric pain, nausea, and a burning sensation in the chest, particularly after meals. Physical examination revealed epigastric tenderness and clinical signs suggestive of anemia, including pallor and fatigue. A detailed clinical history and symptom pattern strongly supported a diagnosis of GERD. Given the classic presentation and absence of alarm features, a non-invasive, symptom-based diagnostic approach was adopted, avoiding the need for endoscopy or pH monitoring. The patient was managed with a combination of pharmacological therapy omeprazole (a proton pump inhibitor), antacids for symptomatic relief, paracetamol for pain management, and vitamin B6 to address nutritional deficiencies. Additionally, lifestyle modifications were emphasized, including dietary regulation, avoidance of trigger foods (such as spicy and acidic items), elevation of the head during sleep, and meal timing adjustments. Within one week of initiating treatment, the patient reported significant improvement in symptoms, with reduced frequency and intensity of heartburn and nausea. This case highlights the importance of early recognition and comprehensive management of GERD, especially in young adults with a chronic history of symptoms. It underscores the effectiveness of combining pharmacological treatment with lifestyle interventions and demonstrates that a symptom-based, non-invasive approach can be both practical and effective in primary care settings. Patient education and adherence to therapy remain critical in preventing recurrence and improving long-term outcomes.

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Journal Info

Abbrev

brtl

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Nursing

Description

Biomedical Research and Theory Letters (BRTL) is an international peer‑reviewed journal dedicated to advancing the frontiers of biomedical science through the integration of theory, experimentation, and clinical application. The journal provides a platform for disseminating high‑quality research ...