Background: S. aureus and S. pyogenes are Gram-positive bacteria that are the main causes of impetigo, a skin infection marked by a red rash. Impetigo is commonly treated with antibiotics, but long-term use risks side effects, so a complementary alternative such as green tea leaf extract (Camellia sinensis) is needed. Aim: To determine the effect of liquid soap containing 7%, 10%, and 13% green tea extract on the inhibition zone of S. aureus and S. pyogenes. Methods: A true experimental study with a post-test-only with control group design used five treatment groups. Inhibition zone diameters were measured with a caliper and analysed using one-way ANOVA with Games-Howell post-hoc comparisons and Mann-Whitney to compare the inhibition zones between the two bacterial species. Results: The 10% concentration produced the highest mean inhibition zone, 5.53 mm against S. aureus and 6.33 mm against S. pyogenes (moderate category), significantly larger than the negative control (p<0.05) but still below the tetracycline positive control. No significant difference was found between the two species (p=0.381). Conclusion: Green tea extract liquid soap shows moderate antibacterial activity against S. aureus and S. pyogenes, with comparable potential against both pathogens as a topical complementary therapy for impetigo.
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