Management Information Systems (MIS) play a strategic role in supporting organizational management in the era of digital transformation. MIS integrates people, procedures, data, and technology to produce accurate, relevant, and timely information for managerial decision-making. This article aims to examine the basic concepts, principles, development, and application of Management Information Systems across various organizational sectors. The research method uses a conceptual literature review by analyzing MIS theories and practices, including historical development, system development models, cross-sector applications, and implementation challenges in the digital era. The results indicate that MIS functions not only as an operational tool but also as a core foundation for organizational digital transformation. Integration with modern technologies such as cloud computing, big data, and artificial intelligence enhances efficiency, transparency, and organizational competitiveness. This article is expected to serve as an academic and practical reference for organizations in implementing effective MIS.
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