JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice)
Vol 15, No 4

Adherence to Oral Chemotherapy in Breast Cancer Patients at a Gianyar General Hospital and the Influencing Factors

Yuliawati, Agustina Nila (Unknown)
Simbolon, Ratih Elisabet (Unknown)
Ratnasari, Pande Made Desy (Unknown)



Article Info

Publish Date
31 Dec 2025

Abstract

Background: Breast cancer patients receiving oral chemotherapy must strictly adhere to their treatment regimen for optimal therapeutic outcomes. Various factors, including demographics, environment, social dynamics, and economic circumstances may impact adherence to the recommended treatment.Objectives: This study aims to assess patient’s treatment adherence and decisively identify the factors that affect it.Methods: This cross-sectional study was conducted at a General Hospital in Gianyar, Bali, in May-June 2024, and 70 samples were purposively selected. Patients with complete medical records and consent were recruited; those with incomplete questionnaires were excluded. An adapted questionnaire and data collection sheet were used to measure adherence and gather medical information. The responses to the adherence questionnaire have been effectively processed into a final scoring format. Higher scores clearly reflect better adherence. Then, the data analysis involved univariate tests to examine respondent characteristics and adherence, as well as bivariate tests (Spearman-rho and Mann Whitney U-Test) to analyze the relationship between respondent characteristics and their adherence (with a 95% CI).Results: The majority of respondents were <60 years old (75.71%), female (100%), had completed elementary school (28.57%), were employed (64.29%), lived in rural areas (58.57%), had been diagnosed with cancer for <4 years (100%) with stage 3 cancer (47.14%), underwent oral chemotherapy ≤3 times a month (71.43%), had no comorbidities (78.57%), used national health insurance (100%), and had an average adherence score of 88.77±3.72 (moderate of adherence). None of the respondent characteristics mentioned in the results of the respondent description were related to patient adherence (p>0.005).Conclusion: The patient's adherence to oral chemotherapy is moderate. Other factors suspected to strongly influence better adherence to treatment include consistent treatment monitoring by pharmacists, family support, knowledge, health insurance, and the patient's psychological condition.

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Journal Info

Abbrev

jmpf

Publisher

Subject

Health Professions Medicine & Pharmacology Public Health

Description

JMPF is the first open access journal in Indonesia specialized in both research of pharmaceutical management and pharmacy practice. Articles submitted in JMPF are peer reviewed, we accept review articles and original research articles with no submission/publication fees. JMPF receives manuscripts ...