ODONTO Dental Journal
Vol 12, No 3 (2025): December 2025

Antibacterial Effectiveness Of Green Shell Nanocitosan (Perna Viridis) On The Growth Of The Bacteria Prevotella Intermedia (In Vitro Study)

Widyastuti, Noor Hafida (Unknown)
Cahyani, Cahyani (Unknown)



Article Info

Publish Date
31 Dec 2025

Abstract

Background: Green mussel shell nanochitosan is a size modification of chitosan obtained from green mussel shells that have been processed with specific standards. Nanochitosan from green mussel shells has not been researched for its anti-bacterial properties against Prevotella intermedia  bacteriaPurpose: This study aims to determine the antibacterial effect on the growth of Prevotella intermedia bacteria. Method: This research is laboratory research using a posttest only control group design.Method: This research is laboratory research using a posttest only control group designResult: Nanochitosan with concentrations of 0.5%, 1%, 1.5% and 2% was able to inhibit the growth of Prevotella intermedia bacteria. The test results using the One Way ANOVA test obtained a value of p = 0.000 so that p < 0.5 and it was stated that there was a significant difference between treatment groups on the growth inhibition value of Prevotella intermedia bacteriaConclusion: There is an anti-bacterial effect and there is an inhibitory zone in the culture of Prevotella intermedia bacteria that has been incubated within 24 hours with 37°C. The greater the concentration used, the more effective the antibacterial agent is 

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