International Journal of Health Science
Vol. 5 No. 1 (2025): : International Journal of Health

Lunasin's Mechanism as an Antioxidant and Hypocholesterolemic Agent

Santi Widiasari (Universitas Abdurrab,)
Sabrina Hayati (Universitas Abdurrab)
May Valzon (Universitas Abdurrab)
Wahyu Ramadhan (Universitas Abdurrab)



Article Info

Publish Date
19 Aug 2025

Abstract

Several ways that can help lower cholesterol levels in the blood include using drugs (pharmacotherapy) or by modifying lifestyle and consuming certain foods. One of them is lunasin. Lunasin is a peptide found in soybean plants and is a promising drug candidate because it has broad health effects such as antioxidant, anti-inflammatory, anti-cancer, and lowering blood cholesterol through various mechanisms. This paper aims to examine the role and mechanism of action of lunasin as an antioxidant and its ability to lower blood cholesterol levels due to the unique peptide structure of lunasin as well as the bioavailability of lunasin starting from degradation, absorption, translocation and distribution of lunasin to target organs or target tissues after oral administration . This paper also discusses soybean plants as the main source of lunasin and the optimal content of lunasin in soybeans.

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Journal Info

Abbrev

ijhs

Publisher

Subject

Health Professions Public Health Social Sciences

Description

International Journal of Health Science, This journal publishes articles on practice, theory, and research in all areas of health, including: Surgical Medical Practice, Pharmacy, Maternity, Child Health, Mental Health, Public Health, Dental, Medical Education, Midwifery, Medicine and Nursing, Health ...